Some clinical trials found to be biased
Tue, 06/30/2009 - 20:36 — frank
During the past two decades, the pharmaceutical industry has gained unprecedented control over the evaluation of its own products as less money has been available from academic and governmental sources for clinical research. Today drug companies finance most clinical studies of prescription drugs, spending $84 billion yearly on drug development in an attempt to capture as much of the annual $162 billion prescription market as possible. Read More...
As proteins are dynamic in nature, they are constantly changing their conformations. Certain conformations enhance the rate of a reaction more than others which we describe as being more enzymatically active. Here’s the important part. This means that just the smallest change in structure or orientation of any part of this protein has dramatic effects on its enzymatic activity and, consequently, our health.